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Primate Research at the Univ. of Alabama at Birmingham information=
=20
provided by Alabama Voice for Animals
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Primate Research at the Univ. of Alabama at Birmingham information=
=20
provided by Alabama Voice for Animals
Primate
Research at the
Univ. of Alabama =
at
Birmingham
information provided by
Alabama Voice for Animals
According to the
University’s 2002 USDA/APHIS report, UAB houses 360 primates. In 2004, Alabama Voice for
Animals used Ala=
bama’s
Open Records Act to obtain documents relating to primate research at UAB. We have learned much a=
bout
the nature of prima=
te
research at UAB from the descriptions of experimental plans and procedures. Below are a =
few
examples of t=
he
research being conducted on primates at UAB:
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Primate Research at the Univ. of Alabama at Birmingham information=
=20
provided by Alabama Voice for Animals
<=
/span>
The
project titled FMR Imaging of t=
he Eye
Stabilization Process is an <=
/span> =
extremely invasive experiment that involves not on=
ly
multiple surgeries, but also
water deprivation. The animals are subjected to a great deal of routine =
span> handling and daily confinement to a restraint chai=
r,
both of which are highly stressful
for the primate. Also as part of the experiment, the primate is subjected to time in the magnetic bore of an fMRI
machine.
To prepare the primate for the
experiment, the Principle Investigator first performs a series of surgeries which allow him to =
bolt
recording devices onto the
animal’s skull. Two metal strips to which a head restraint bar will =
be =
attached are bolted onto the primate’s skull=
. Later, holes are bored into the <=
/span> =
monkey’s skull to allow electrodes to be fed=
into
the animal’s brain. Teflon coated
metal coils are implanted behind the primates eyes.
The
experiment also calls for a rigid water restriction regime in which the =
span> =
primate is denied water for 20 hours each day for =
5 day
blocks. During experim=
ental
procedures, the primate is confined to a restraint chair for 3 to 5 <=
span
style=3D'font-size:50%'>hours. The head restraint pole embedded in his sku=
ll is
bolted to the chair to immobilize
his head. Water is given during this time as a reward for good =
behavior. When the procedure is over and the prima=
te is
returned to his home ca=
ge,
water is again withheld for the next 20 hours.
At the =
end of
the experiment, the primates are exsanguinated—bled to death. =
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Primate Research at the Univ. of Alabama at Birmingham information=
=20
provided by Alabama Voice for Animals
In the experiment Evaluation of Brain Death on Islet Recovery =
and Functionality in Primates experimenters insert catheters into =
the skull of a monkey. By inflating a small balloon
within the catheter, they a=
re
able to increase the pressure within the head and cause a rapidly progressive brain injury which leads to br=
ain
death. After brain =
death
is achieved, but before =
the animal is killed, the scientists open the primate’s abdomen and remove his
pancreas.
~~~~~~~~~~~~~~
In the experiment A New Approach to the Xenotransplantation in=
Primates genetically modified
pancreatic cells from pigs are transplanted
into the livers of primates. A large midline incision is must be performed on the primate as part of the
transplant. Despite <=
/span>the highly invasive nature of this procedure, anal=
gesics
are only given for three da=
ys
following the surgery. After the transplants, the animals are also subjected to liver biopsies and l=
ymph
node biopsies as well=
.
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Primate Research at the Univ. of Alabama at Birmingham information=
=20
provided by Alabama Voice for Animals
From
the necropsy reports , we have learned a great deal about the suffering=
of individual primates at UAB:
=
• According to this monkey’s necropsy report, “he was a self
mutilator with an exten=
ded
period of lesion healing and re-injury. Self injurious behavior is a serio=
us
indication of behavioral
disturbance and stress often exhibited by singly housed primates. Isolatio=
n is
extremely distressful for
primates.
• ID # RQ2820: Another monkey=
, a 3
year old rhesus macaque suffered from chronic colitis. The overall poor condition of his
Gastro-Intestinal tract mirrors the “necropsies of several of these undersized young macaques with
multiple bouts of diarrhea, weight loss and general failure to thrive.” Undersized primates with chronic
colitis are clearly very unhealthy
and this condition sounds as if it is rather common.
• A 2 year old female macaque, primat=
e ID#
CP7B, was found to be “in poor health.”
The veterinarian found that she was “both too small and too thin.=
221;
Due to chronic infla=
mmation
of the Gastro Intestinal tract, she was treated for inflammatory bowel
disease, although the cond=
ition
persisted until her death.
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Primate Research at the Univ. of Alabama at Birmingham information=
=20
provided by Alabama Voice for Animals
• Primate ID# APIK was infected with a Simian (monkey)- Human Immunodeficiency Virus, or SHIV. He was reported t=
o be
“emaciated.” The chronic
diarrhea and weight loss experienced by this monkey “are among the <=
/span> expected outcomes of this experimental
manipulation.”
•
• Primate ID# CP6J d=
ied
after surgery, while she was recovering from anesthesia. According to her necropsy report, R=
20;she
was breathing unassisted post anesthesia.
She started coughing blood on extubation.”
•
• One primate, ID# 98P162 =
, was
infected with SIV, a monkey form of HIV. In his necropsy report, it is noted that he was lame in l=
eft
leg with a swollen ankle. The resulting
disuse of his limb led to arthritis and atrophy of the muscle and bone.
·
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------=_NextPart_01C5EE06.EBFBA840
Content-Location: file:///C:/B1346082/uab_files/script.js
Content-Transfer-Encoding: quoted-printable
Content-Type: application/javascript; charset="us-ascii"
function LoadSld()
{
var sld=3DGetObj("SlideObj")
if( !g_supportsPPTHTML ) {
sld.style.visibility=3D"visible"
return
}
if( MakeNotesVis() ) return
runAnimations =3D _InitAnimations();
if( IsWin("PPTSld") )
parent.SldUpdated(GetSldId())
g_origSz=3DparseInt(SlideObj.style.fontSize)
g_origH=3Dsld.style.posHeight
g_origW=3Dsld.style.posWidth
g_scaleHyperlinks=3D(document.all.tags("AREA").length>0)
if( g_scaleHyperlinks )
InitHLinkArray()
if( g_scaleInFrame||(IsWin("PPTSld") && parent.IsFullScrMode() ) )
document.body.scroll=3D"no"
_RSW()
if( IsWin("PPTSld") && parent.IsFullScrMode() )
FullScrInit();
=09
MakeSldVis();
ChkAutoAdv()
if( runAnimations )
{
if( document.all("NSPlay") )
document.all("NSPlay").autoStart =3D false;
if( sld.filters && sld.filters.revealtrans )
setTimeout( "document.body.start()", sld.filters.revealtrans.duration * =
1000 );
else
document.body.start();
}
}
function MakeSldVis()
{
var fTrans=3Dg_showAnimation && SldHasTrans()
if( fTrans )
{
if( g_bgSound ) {
idx=3Dg_bgSound.indexOf(",");
pptSound.src=3Dg_bgSound.substr( 0, idx );
pptSound.loop=3D -(parseInt(g_bgSound.substr(idx+1)));
}
SlideObj.filters.revealtrans.Apply()
}
SlideObj.style.visibility=3D"visible"
if( fTrans )
SlideObj.filters.revealtrans.Play()
}
function MakeNotesVis()
{
if( !IsNts() ) return false
SlideObj.style.display=3D"none"
nObj =3D document.all.item("NotesObj")
parent.SetHasNts(0)
if( nObj ) {
nObj.style.display=3D""
parent.SetHasNts(1)
}
return 1
}
function ChkAutoAdv()
{
if(SldHasTrans())
SlideObj.onfilterchange=3DAutoAdv
else
AutoAdv()
}
function AutoAdv()
{
if(!IsWin("PPTSld") || !gUseSldTimings )return
var sld=3DGetCurSld()
if( (sld.mAdvDelay>0) && !parent.IsFramesMode() )
setTimeout("parent.GoToNextSld()",sld.mAdvDelay)
}
function GetObj(id)
{
if(g_supportsPPTHTML) return document.all(id);
else return document.getElementById(id);
}
function SldHasTrans() { return SlideObj.style.getAttribute("filter")!=3D""=
}
function GetSldId() { return sId=3Dlocation.href.substring(location.href.la=
stIndexOf('/')+1) }
function HideMenu() { if( frames["PPTSld"] && PPTSld.document.all.item("ctx=
tmenu") && PPTSld.ctxtmenu.style.display!=3D"none" ) { PPTSld.ctxtmenu.styl=
e.display=3D'none'; return true } return false }
function IsWin( name ) { return window.name =3D=3D name }
function IsNts() { return IsWin("PPTNts") }
function IsSldOrNts() { return( IsWin("PPTSld")||IsWin("PPTNts") ) }
function SupportsPPTAnimation() { return( navigator.platform =3D=3D "Win32"=
&& navigator.appVersion.indexOf("Windows")>0 ) }
function SupportsPPTHTML()
{
var appVer=3Dnavigator.appVersion, msie=3DappVer.indexOf("MSIE "), ver=3D0
if( msie >=3D 0 )
ver=3DparseFloat( appVer.substring( msie+5, appVer.indexOf(";",msie) ) )
else
ver=3DparseInt(appVer)
return( ver >=3D 4 && msie >=3D 0 )
}
function _RSW()
{
if( !g_supportsPPTHTML || IsNts() ||
( !g_scaleInFrame && (!IsWin("PPTSld") || !parent.IsFullScrMode()) ) )
return
var padding=3D0;
if( IsWin("PPTSld") && parent.IsFramesMode() ) padding=3D6
cltWidth=3Ddocument.body.clientWidth-padding
cltHeight=3Ddocument.body.clientHeight-padding
factor=3D(1.0*cltWidth)/g_origW
if( cltHeight < g_origH*factor )
factor=3D(1.0*cltHeight)/g_origH
newSize =3D g_origSz * factor
if( newSize < 1 ) newSize=3D1
s=3DSlideObj.style
s.fontSize=3DnewSize+"px"
s.posWidth=3Dg_origW*factor
s.posHeight=3Dg_origH*factor
s.posLeft=3D(cltWidth-s.posWidth+padding)/2
s.posTop=3D(cltHeight-s.posHeight+padding)/2
if( g_scaleHyperlinks )
ScaleHyperlinks( factor )
}
function _InitAnimations()
{
animRuntimeInstalled =3D ''+document.body.localTime !=3D 'undefined';
isFullScreen =3D (window.name =3D=3D "PPTSld") && !parent.IsFramesMode();
g_animUseRuntime =3D g_showAnimation && animRuntimeInstalled && !(isFullSc=
reen && parent.IsSldVisited());
if( g_animUseRuntime ) {
collSeq =3D document.all.tags("seq");
if( collSeq !=3D null ) {
for(ii=3D0;ii
numSlds )
gSldJumpIdx =3D numSlds;
if ( gSldJumpIdx >=3D 0 ) {
if ( gSldJumpIdx =3D=3D 0 )
gSldJumpIdx =3D 1;
var jumpTo =3D parseInt(gSldJumpIdx);
gSldJump =3D 0; gSldJumpIdx =3D "";
win.GoToSld( parent.GetSldList().mList[jumpTo-1].mSldHref )
}
}
}
function _KDH()
{
if( event.keyCode =3D=3D 8 ) {
event.returnValue =3D 0;
parent.GoToPrevSld();
}
}
function DocumentOnClick()
{
if( IsNts() || parent.HideMenu() ) return;
if( ( g_allowAdvOnClick && !parent.IsFramesMode() ) ||
(event && (event.keyCode=3D=3D32) ) )
parent.GoToNextSld();
}
var g_supportsPPTHTML =3D SupportsPPTHTML(), g_scaleInFrame =3D 1, gId=3D""=
, g_bgSound=3D"",
g_scaleHyperlinks =3D false, g_allowAdvOnClick =3D 1, g_showInBrowser =
=3D 0, gLoopCont =3D 0, gUseSldTimings =3D 1;
var g_showAnimation =3D g_supportsPPTHTML && SupportsPPTAnimation() && ( (w=
indow.name=3D=3D"PPTSld" && !parent.IsFramesMode()) || g_showInBrowser );va=
r g_animManager =3D null;
var g_animUseRuntime =3D false;
var g_animItemsToHide, g_animInteractiveItems, g_animSlideTime;
var g_animMainSequence =3D null;
var ENDSHOW_MESG=3D"End of slide show, click to exit.", SCREEN_MODE=3D"Fram=
es", gIsEndShow=3D0, NUM_VIS_SLDS=3D5, SCRIPT_HREF=3D"script.js", FULLSCR_H=
REF=3D"fullscreen.htm";
var gCurSld =3D gPrevSld =3D 1, g_offset =3D 0, gNtsOpen =3D gHasNts =3D gO=
tlTxtExp =3D 0, gHasNarration =3D 0, gOtlOpen =3D true
window.gPPTHTML=3DSupportsPPTHTML()
var gMainDoc=3Dnew Array(new hrefList("slide0001.htm",1,-1,1),new hrefList(=
"slide0003.htm",1,-1,1),new hrefList("slide0004.htm",1,-1,1),new hrefList("=
slide0005.htm",1,-1,1),new hrefList("slide0006.htm",1,-1,1));
function FullScrInit()
{
g_allowAdvOnClick =3D GetCurSld().mAdvOnClk
document.body.style.backgroundColor=3D"black"
document.oncontextmenu=3Dparent._CM;
document.onkeydown =3D _KDH;
document.ondragstart=3DCancel
document.onselectstart=3DCancel
self.focus()
}
function Redirect( frmId )
{
var str=3Ddocument.location.hash,idx=3Dstr.indexOf('#'), sId=3DGetSldId()
if(idx>=3D0) str=3Dstr.substr(1);
if( window.name !=3D frmId && ( sId !=3D str) ) {
obj =3D GetObj("Main-File")
window.location.href=3Dobj.href+"#"+sId
return 1
}
return 0
}
var MHTMLPrefix =3D CalculateMHTMLPrefix();
function CalculateMHTMLPrefix()
{
if ( document.location.protocol =3D=3D 'mhtml:') {
href=3Dnew String(document.location.href)
Start=3Dhref.indexOf('!')+1
End=3Dhref.lastIndexOf('/')+1
if (End < Start)
return href.substring(0, Start)
else
return href.substring(0, End)
}
return '';
}
function GetTags(base,tag)
{
if(g_supportsPPTHTML) return base.all.tags(tag);
else return base.getElementsByTagName(tag);
}
function UpdNtsPane(){ if(frames["PPTNts"]) PPTNts.location.replace( MHTMLP=
refix+GetHrefObj( gCurSld ).mNtsHref ) }
function UpdNavPane( sldIndex ){ if(gNavLoaded) PPTNav.UpdNav() }
function UpdOtNavPane(){ if(gOtlNavLoaded) PPTOtlNav.UpdOtlNav() }
function UpdOtlPane(){ if(gOtlLoaded) PPTOtl.UpdOtl() }
function SetHasNts( fVal )
{
if( gHasNts !=3D fVal ) {
gHasNts=3DfVal
UpdNavPane()
}
}
function ToggleOtlText()
{
gOtlTxtExp=3D!gOtlTxtExp
UpdOtlPane()
}
function ToggleOtlPane()
{
frmset=3Ddocument.all("PPTHorizAdjust")
frm=3Ddocument.all("PPTOtl")
if( gOtlOpen )
frmset.cols=3D"*,100%"
else
frmset.cols=3D"25%,*"
gOtlOpen=3D!gOtlOpen
frm.noResize=3D!frm.noResize
UpdOtNavPane()
}
function ToggleNtsPane()
{
frmset=3Ddocument.all("PPTVertAdjust")
frm=3Ddocument.all("PPTNts")
if( gNtsOpen )
frmset.rows=3D"100%,*"
else
frmset.rows=3D"*,20%"
gNtsOpen=3D!gNtsOpen
UpdNtsPane()
}
function ClearMedia()
{
if (PPTSld.pptSound) PPTSld.pptSound.loop =3D 0;
}
function FullScreen()
{
if ( PPTSld.g_animUseRuntime )
PPTSld.document.body.pause();
ClearMedia();
var href =3D ( document.location.protocol =3D=3D 'mhtml:') ? FULLSCR_HREF =
: FULLSCR_HREF+"#"+GetHrefObj(gCurSld).mSldHref;
if(PPTNav.event.ctrlKey) {
var w =3D (window.screen.availWidth * 1.0) / 2.0
var h =3D w * (PPTSld.g_origH * 1.0) / PPTSld.g_origW
win =3D window.open( MHTMLPrefix+href,null,"toolbar=3D0,resizable=3D1,top=
=3D0,left=3D0," + "width=3D"+ w + ",height=3D" + h );
if( PPTSld.g_animUseRuntime )
win.document.body.PPTSldFrameset=3Dwindow;
}
else
{
win =3D window.open( MHTMLPrefix+href,null,"fullscreen=3Dyes" );
if( PPTSld.g_animUseRuntime )
win.document.body.PPTSldFrameset=3Dwindow;
}
}
function ToggleVNarration()
{
rObj=3DPPTSld.document.all("NSPlay")
if( rObj && !PPTSld.g_animUseRuntime ) {
if( (rObj.playState =3D=3D 1)||(rObj.playState =3D=3D 0) )
rObj.Play()
else if( rObj.playState =3D=3D 2 )
rObj.Pause()
else
return;
}
else if( PPTSld.g_animUseRuntime )
{
narObj =3D PPTSld.document.all("narrationID")
if( narObj )
narObj.togglePause()
}
}
function GetCurSldNum()
{
obj=3DGetHrefObj(gCurSld)
if( obj.mOrigVis =3D=3D 1 )
return obj.mSldIdx
else
return gCurSld
}
function GetNumSlds()
{
if( GetHrefObj(gCurSld).mOrigVis =3D=3D 1 )
return GetSldList().mNumVisSlds;
else
return GetSldList().mList.length
}
function GetSldNum( href )
{
for(ii=3D0; ii 1 )
PopSldList();
else if( !IsFramesMode() ) {
if( gLoopCont )
GoToFirst()
else
EndShow()
}
}
function GoToPrevSld()
{
ii=3DgCurSld-1
if( ii > 0 ) {
obj=3DGetHrefObj(ii)
while ( obj && ( obj.mVis =3D=3D 0 ) && ( ii>0 ) )
obj=3DGetHrefObj(--ii)
if( ii =3D=3D 0 ) ii=3D1
GoToSldNum(ii)
}
}
function GoToFirst(){ GoToSld( GetHrefObj(1).mSldHref ) }
function GoToLast()
{
ii=3DGetSldList().mList.length
if( ii !=3D gCurSld )
GoToSld( GetHrefObj(ii).mSldHref )
}
function GoToSldNum( num )
{
if( PPTSld.event ) PPTSld.event.cancelBubble=3Dtrue
obj =3D GetHrefObj( num )
obj.mVis=3D1
gPrevSld=3DgCurSld
gCurSld =3D num;
PPTSld.location.replace(MHTMLPrefix+obj.mSldHref)
if( IsFramesMode() ) {
UpdNavPane(); UpdOtlPane(); UpdNtsPane()
}
}
function GoToSld( href )
{
if( PPTSld.event ) PPTSld.event.cancelBubble=3Dtrue
GetHrefObj( GetSldNum(href) ).mVis=3D1
PPTSld.location.replace(MHTMLPrefix+href)
}
function SldUpdated( id )
{
if( id =3D=3D GetHrefObj(gCurSld).mSldHref ) return
gPrevSld=3DgCurSld
gCurSld=3DGetSldNum(id)
if( IsFramesMode() ) {
UpdNavPane(); UpdOtlPane(); UpdNtsPane()
}
}
function PrevSldViewed(){ GoToSld( GetHrefObj(gPrevSld).mSldHref ) }
function HasPrevSld() { return ( gIsEndShow || ( gCurSld !=3D 1 && GetHrefO=
bj( gCurSld-1 ).mVis =3D=3D 1 )||( GetCurSldNum() > 1 ) ) }
function HasNextSld() { return (GetCurSldNum() !=3D GetNumSlds()) }
function CloseWindow() {
if( HideMenu() ) return;
var event =3D PPTSld.event;
if( !IsFramesMode() && event && (event.keyCode=3D=3D27 || event.keyCode=3D=
=3D32 || event.type=3D=3D"click" ) )
window.close( self );
CatchNumKeys( self, event );
}
function Unload() { gIsEndShow=3D0; }
function SetupEndShow() {
gIsEndShow=3D1;
PPTSld.document.body.scroll=3D"no";
PPTSld.document.onkeypress=3DCloseWindow;
PPTSld.document.onclick=3DCloseWindow;
PPTSld.document.oncontextmenu=3D_CM;
}
function EndShow()
{
if( IsFramesMode() ) return
if( PPTSld.event ) PPTSld.event.cancelBubble=3Dtrue
doc=3DPPTSld.document
doc.open()
doc.writeln('' + ENDSHOW_MESG + '
')
doc.close()
}
function SetSldVisited(){ GetSldList().mList[gCurSld-1].mVisited=3Dtrue }
function IsSldVisited(){ return GetSldList().mList[gCurSld-1].mVisited }
function hrefList( sldHref, visible, advDelay, advClk )
{
this.mSldHref=3D this.mNtsHref =3D sldHref
this.mOrigVis=3D this.mVis =3D visible
this.mVisited=3D false
this.mAdvDelay=3D advDelay
this.mAdvOnClk=3D advClk
}
function SldList(arr,curSld,fEnd)
{
this.mCurSld =3D curSld;
this.mList =3D new Array();
var idx =3D 1;
for(ii=3D0;ii 0) {
PushSldList(sldList,fEnd);
gCurSld =3D 1;
}
else
if( PPTSld.event ) PPTSld.event.cancelBubble=3Dtrue
}
function PushSldList(arr,fEnd) {
var ii =3D gSldStack.length;
gSldStack[ii] =3D new SldList(arr,gCurSld,fEnd);
GoToSld( gSldStack[ii].mList[0].mSldHref );
}
function PopSldList() {
if (gSldStack[gSldStack.length-1].fEndShow)
EndShow()
else {
gCurSld =3D gSldStack[gSldStack.length-1].mCurSld;
gSldStack[gSldStack.length-1] =3D null;
gSldStack.length--;
var sldList =3D gSldStack[gSldStack.length-1];
GoToSld( sldList.mList[gCurSld - 1].mSldHref );
}
}
var custShowList=3Dnew Array();
function ImgBtn( oId,bId,w,action )
{
var t=3Dthis
t.Perform =3D _IBP
t.SetActive =3D _IBSetA
t.SetInactive=3D _IBSetI
t.SetPressed =3D _IBSetP
t.SetDisabled=3D _IBSetD
t.Enabled =3D _IBSetE
t.ChangeIcon =3D null
t.UserAction =3D action
t.ChgState =3D _IBUI
t.mObjId =3D oId
t.mBorderId=3D bId
t.mWidth =3D w
t.mIsOn =3D t.mCurState =3D 0
}
function _IBSetA()
{
if( this.mIsOn ) {
obj=3Dthis.ChgState( gHiliteClr,gShadowClr,2 )
obj.style.posTop=3D0
}
}
function _IBSetI()
{
if( this.mIsOn ) {
obj=3Dthis.ChgState( gFaceClr,gFaceClr,1 )
obj.style.posTop=3D0
}
}
function _IBSetP()
{
if( this.mIsOn ) {
obj=3Dthis.ChgState( gShadowClr,gHiliteClr,2 )
obj.style.posLeft+=3D1; obj.style.posTop+=3D1
}
}
function _IBSetD()
{
obj=3Dthis.ChgState( gFaceClr,gFaceClr,0 )
obj.style.posTop=3D0
}
function _IBSetE( state )
{
var t=3Dthis
GetObj( t.mBorderId ).style.visibility=3D"visible"
if( state !=3D t.mIsOn ) {
t.mIsOn=3Dstate
if( state )
t.SetInactive()
else
t.SetDisabled()
}
}
function _IBP()
{
var t=3Dthis
if( t.mIsOn ) {
if( t.UserAction !=3D null )
t.UserAction()
if( t.ChangeIcon ) {
obj=3DGetObj(t.mObjId)
if( t.ChangeIcon() )
obj.style.posLeft=3Dobj.style.posLeft+(t.mCurState-4)*t.mWidth
else
obj.style.posLeft=3Dobj.style.posLeft+(t.mCurState-0)*t.mWidth
}
t.SetActive()
}
}
function _IBUI( clr1,clr2,nextState )
{
var t=3Dthis
SetBorder( GetObj( t.mBorderId ),clr1,clr2 )
obj=3DGetObj( t.mObjId )
obj.style.posLeft=3Dobj.style.posLeft+(t.mCurState-nextState)*t.mWidth-obj=
.style.posTop
t.mCurState=3DnextState
return obj
}
function TxtBtn( oId,oeId,action,chkState )
{
var t=3Dthis
t.Perform =3D _TBP
t.SetActive =3D _TBSetA
t.SetInactive=3D _TBSetI
t.SetPressed =3D _TBSetP
t.SetDisabled=3D _TBSetD
t.SetEnabled =3D _TBSetE
t.GetState =3D chkState
t.UserAction =3D action
t.ChgState =3D _TBUI
t.mObjId =3D oId
t.m_elementsId=3D oeId
t.mIsOn =3D 1
}
function _TBSetA()
{
var t=3Dthis
if( t.mIsOn && !t.GetState() )
t.ChgState( gHiliteClr,gShadowClr,0,0 )
}
function _TBSetI()
{
var t=3Dthis
if( t.mIsOn && !t.GetState() )
t.ChgState( gFaceClr,gFaceClr,0,0 )
}
function _TBSetP()
{
if( this.mIsOn )
this.ChgState( gShadowClr,gHiliteClr,1,1 )
}
function _TBSetD()
{
this.ChgState( gFaceClr,gFaceClr,0,0 )
this.mIsOn =3D 0
}
function _TBSetE()
{
var t=3Dthis
if( !t.GetState() )
t.ChgState( gFaceClr,gFaceClr,0,0 )
else
t.ChgState( gShadowClr,gHiliteClr,1,1 )
t.mIsOn =3D 1
}
function _TBP()
{
var t=3Dthis
if( t.mIsOn ) {
if( t.UserAction !=3D null )
t.UserAction()
if( !t.GetState )
return
if( t.GetState() )
t.SetPressed()
else
t.SetActive()
}
}
function _TBUI( clr1,clr2,lOffset,tOffset )
{
SetBorder( GetObj( this.mObjId ),clr1,clr2 )
Offset( GetObj( this.m_elementsId ),lOffset,tOffset )
}
function Offset( obj, top, left ){ obj.style.top=3Dtop; obj.style.left=3Dle=
ft }
function SetBorder( obj, upperLeft, lowerRight )
{
s=3Dobj.style;
s.borderStyle =3D "solid"
s.borderWidth =3D 1
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Primate Research at the Univ. of Alabama at Birmingham information=
=20
provided by Alabama Voice for Animals
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Notes
1
According to the University’s 2002 USDA/APHIS report, UAB hous=
es
360 primates. In 2004, Alabama Voice for Animals used Alabama’s
Open Records Act to obtain documents relating to primate research at
UAB. We have learned much about the nature of primate research at UAB
from the descriptions of experimental plans and procedures. Below ar=
e a
few examples of the research being conducted on primates at UAB:
2
The project titled FMR Imaging of the Eye Stabilization Process is an
extremely invasive experiment that involves not only multiple surger=
ies,
but also water deprivation. The animals are subjected to a great dea=
l of
routine handling and daily confinement to a restraint chair, both of
which are highly stressful for the primate. Also as part of the
experiment, the primate is subjected to time in the magnetic bore of=
an
fMRI machine.
To prepare the primate=
for
the experiment, the Principle Investigator first performs a series of
surgeries which allow him to bolt recording devices onto the
animal’s skull. Two metal strips to which a head restraint bar
will be attached are bolted onto the primate’s skull. Later, holes are bored into=
the
monkey’s skull to allow electrodes to be fed into the
animal’s brain. Teflon coated metal coils are implanted behind=
the
primates eyes.
The experiment also calls for a rigid water restriction regime in wh=
ich
the primate is denied water for 20 hours each day for 5 day blocks.
During experimental procedures, the primate is confined to a restrai=
nt
chair for 3 to 5 hours. The head restraint pole embedded in his skul=
l is
bolted to the chair to immobilize his head. Water is given during th=
is
time as a reward for good behavior. When the procedure is over and t=
he
primate is returned to his home cage, water is again withheld for the
next 20 hours.
At the end of the experiment, the primates are exsanguinated—b=
led
to death.
3
In the experiment Evaluation of Brain Death on Islet Recovery and
Functionality in Primates experimenters insert catheters into the sk=
ull
of a monkey. By inflating a small balloon within the catheter, they =
are
able to increase the pressure within the head and cause a rapidly
progressive brain injury which leads to brain death. After brain dea=
th
is achieved, but before the animal is killed, the scientists open the
primate’s abdomen and remove his pancreas.
~~~~~~~~~~~~~~
In the experiment A New Approach to the Xenotransplantation in Prima=
tes genetically
modified pancreatic cells from pigs are transplanted into the livers=
of
primates. A large midline incision is must be performed on the prima=
te
as part of the transplant.
Despite the highly invasive nature of this procedure, analges=
ics
are only given for three days following the surgery. After the
transplants, the animals are also subjected to liver biopsies and ly=
mph
node biopsies as well.
4
From the necropsy reports, we have learned a great deal about the
suffering of individual primates at UAB:
5
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