Primate Freedom Project - Education, Advocacy, Support Primate Freedom Project - Education, Advocacy, Support
These are life stories of primates held in U.S. primate laboratories. They are based on documents obtained from the labs.
Dover Chimpanzee
Sellers Chimpanzee
3566 Rhesus Macaque
PWc2 Rhesus Macaque
Unknown Rhesus Macaque
13481 Rhesus Macaque
14326 Rhesus Macaque
20213 Rhesus Macaque
20229 Rhesus Macaque D
20233 Rhesus Macaque
20247 Rhesus Macaque
20253 Rhesus Macaque
20346 Rhesus Macaque
23993 Squirrel Monkey
23915 Crab-eating Macaque
23954 Rhesus Macaque
25142 Crab-eating Macaque
24974 Rhesus Macaque
24013 Squirrel Monkey
25157 Crab-eating Macaque
25205 Crab-eating Macaque
25274 Rhesus Macaque
25412 Crab-eating Macaque
27276 Crab-eating Macaque
28100 Crab-eating Macaque
28114 Crab-eating Macaque
30914 Rhesus Macaque
30916 Rhesus Macaque
30983 Rhesus Macaque
31031 Rhesus Macaque
cj0233 Common Marmoset
cj0453 Common Marmoset D
cj0495 Common Marmoset
Piotr Rhesus Macaque
rhaf72 Rhesus Macaque
rhao45 Rhesus Macaque
Rh1890 Rhesus Macaque
R80180 Rhesus Macaque
R87083 Rhesus Macaque
R89124 Rhesus Macaque
R89163 Rhesus Macaque
R90128 Rhesus Macaque
R91040 Rhesus Macaque
R93014 Rhesus Macaque
R95054 Rhesus Macaque D
R95065 Rhesus Macaque D
R95076 Rhesus Macaque D
R96108 Rhesus Macaque
R97041 Rhesus Macaque
R97082 Rhesus Macaque
R95100 Rhesus Macaque
S93052 Rhesus Macaque
Response from Jordana Lenon, public relations manager for WNPRC.
A03068 Rhesus Macaque
A98056 Pig-tailed Macaque
A92025 Baboon
F91396 Pig-tailed Macaque D
J90153 Pig-tailed Macaque
J90266 Pig-tailed Macaque
J90299 Crab-eating Macaque
J91076 Pig-tailed Macaque D
J91386 Pig-tailed Macaque D
J91398 Pig-tailed Macaque D
J92068 Pig-tailed Macaque
J92349 Pig-tailed Macaque D
J92476 Pig-tailed Macaque
censored Vervet
censored Vervet
censored Vervet
MCY24525 Crab-eating Macaque
MCY24540 Crab-eating Macaque
OIPM-007 Crab-eating Macaque
UNC-Chapel Hill
3710 Squirrel Monkey
Ashley Chimpanzee
Karla Chimpanzee
Tyson Chimpanzee
Snoy Chimpanzee
Maurice p1 Maurice p2 Chimpanzee
Hercules Chimpanzee
Jerome Chimpanzee
Ritchie Chimpanzee
Rex Chimpanzee
Topsey Chimpanzee
B.G. Chimpanzee
Dawn Chimpanzee
BamBam Chimpanzee
Dixie Chimpanzee
Ginger Chimpanzee
Kelly Chimpanzee
Lennie Chimpanzee
Kist Chimpanzee
Peg Chimpanzee
Aaron Chimpanzee
Chuck Chimpanzee
James Chimpanzee
Alex Chimpanzee
Muna Chimpanzee
Wally Chimpanzee
#1028 Chimpanzee
Lippy Chimpanzee
#1303 Chimpanzee
#CA0127 Chimpanzee
Shane Chimpanzee
The University of Minnesota
#00FP8 Long-Tailed Macaque
#312E Rhesus Macaque
#9711B Rhesus Macaque
#99IP61 Long-tailed Macaque
The Fauna Foundation
The Fauna Foundation Chimpanzees
Center for Biologics Evaluation
Univ. of Alabama - Birmingham


UCD #25205

25205 is a crab-eating macaque; a Macaca fascicularis in the jargon of taxonomy. A cynomolgus monkey, in the jargon of biomedical research laboratories.

25205 was captured in the wild. The day he was caught was the last day he was free to swim, climb, explore crab burrows, socialize, or otherwise behave like a normal crab-eating macaque.

Crab-eating macaques, as their common name implies, often live and forage for food near rivers and coastlines. They feed on fruit and various plant matter, crabs, mollusks, and other small animals exposed during low tide. These monkeys commonly reach into burrows and pull out the crabs and other animals they find inside. They have a fondness for water and can often be seen swimming and diving. They are common in mangrove swamps throughout Southeast Asia. In Bali, they frequent temples and are offered food by the Balinese who regard them as sacred.

Crab-eating macaques live in groups of 20 to 60 individuals. Females generally spend their entire life in the group into which they are born. Males move to new groups as they mature. Macaques are well recognized as living in complex political social hierarchies. They are highly intelligent and are the frequent subjects of brain experiments precisely because their brains, minds, and emotions seem so humanlike.

25205 arrived in Davis, California, at the California Regional Primate Research Center (CRPRC) on January 31, 1990. CRPRC seems to have estimated he was about two years old. He had probably not yet left his natal group when he was captured.

On February 5, 1990 he was injected for the first of over forty times with Ketamine. Ketamine causes hallucinations as well as a burning sensation when injected.

The principal effects are the result of the drug crossing the blood brain barrier, to bind with receptors in the brain. Muscle tone increases. Heart and pulse rate increase. The drug can cause hallucinations, both visual and auditory. The user appears numbed to the outside world. Awareness, although altered, may only be partial. Auditory perception is said to be narrowed. The ability to respond may be limited by muscle spasm and rigidity. The user may appear sedated, if not disturbed by the effects of the drug. Nausea and vomiting may occur. Some degree of paralysis can occur. The effects of the drug may be dependent on environmental factors.

Ketamine use is associated with flashbacks and other psychological problems, which become more frequent with long-term use. Memory loss and dysfunction are common. The development of psychotic illness in vulnerable users is a real danger.

Ketamine can be a very unpleasant drug. It is contraindicated for anyone with a medical history of heart disease, high blood pressure and mental illness.

He was tattooed, given a physical examination – they noted that he had small testicles – had blood drawn, and had a stool sample taken.

After being wormed and immobilized with Ketamine on nine occasions, he was released from quarantine on July 31.

On August 20 they treated him for malaria.

25205 is a monkey who (as of August 22, 2000, when our records for him stop) is never used in one of the macabre or gruesome experiments so common at CRPRC and in other primate labs. In this respect, he has been lucky. On the other hand, his records paint a vivid picture of what daily life is like for a monkey at CRPRC.

On October 10, 1990, they noticed that he had a small wound on his left thumb.

On October 17, they noted that 25205 had a bloody nasal discharge.

On January 14, 1991, it was noted that he had another cut on a finger of his right hand.

It appears, from 25205’s records, that he has never been housed with another monkey. He has been alone now, save for the occasional visits by the humans peering into his cage, for just about a year.

On April 2, someone reports that 25205 has been vomiting. He has been fed almost entirely on monkey chow. The crabs, wild fruit, and other things he used to eat are now simply memories in his dreams perhaps. No longer is he searching the burrows and scampering through the trees looking for food. Now food is placed in his barren cage within easy reach every day. 25205 doesn’t have much to do.

On the 22nd of June, someone notices that part of the pad on his right hand is missing and that he is holding his hand in a guarded position.

On September 13, he is reported to be vomiting again.

On November 27, 1991, he is reported to be having liquid stools.

On January 5, 1992, after about two years at CRPRC he is reported as being depressed, dehydrated, and having diarrhea.

On March 29, he is reported to be vomiting again and to be having intermittent bouts of diarrhea.

On June 2, his rectum prolapsed.

As with all the above maladies, CRPRC personnel provided basic medical care. They often don’t know why he is vomiting or has diarrhea or why his rectum prolapsed, but they do try and treat his symptoms. This, of course, begs the question: if they do not know what is making 25205 ill, if his health is beyond their expertise, his biology beyond their ken, how is it that they can claim to be using monkeys as models of human disease? But this report is about 25205’s life. The question of the scientific validity of animal models of human disease does not belong in his story.

On October 24, he is reported to have an abrasion on a finger of his left hand.

On November 29, he is sneezing, reported to be in “excellent condition,” and perhaps to have an upper respiratory infection.

An odd entry is made in his record on January 27, 1993: “Chaired w/06986 PCP 01.” Exactly what this might mean is subject to speculation since CRPRC is unlikely to say.

Also odd is that the next entry is for January 26. This one notes: “.5cc Ket. Collared for project PCP [unclear]” And the very next entry, for January 27, says: “Electroejaculation (-).”

A pole and collar system is a not uncommon method used to move monkeys who are repeatedly moved, who the staff does not wish to take the time to train (some monkeys are trained to move from one location to another), and who, for some reason they do not want to anesthetize regularly. Basically, a collar is affixed to the monkey. When it is time to move him or her, a pole is attached to the collar from a distance. This allows the monkey to be moved without touching him or her and offers enough distance that the monkey is unable to reach their tormentor.

A primate chair is essentially the chair they are strapped into while being experimented on.

Electroejaculation is a process of shocking the penis in the hopes that the monkey will ejaculate. In this case, the “(-)” might mean that shocking 25205’s penis did not result in an ejaculation.

Recently, researchers at the Oregon Regional Primate Research Center were caught on videotape electroejaculating a monkey there. This undercover video has resulted in public denouncements of the practice by Jane Goodall and others, it resulted in the animal care manager leaving his job, and pointed questions from members of the Oregon State Legislature. Apparently, official reports of the practice weigh less heavily than undercover video aired on T.V.

25205 is part of a study on contraception (Protocol # 8051). The protocol claims:

The cynomolgus monkey was chosen for these types of studies because of it’s size, lack of seasonality and it’s similarity to humans in many aspects of reproductive function. The Primate Testing Facility is a contract supported by NICHD [National Institute of Child Health and Human Development, a part of the U.S. National Institutes of Health] and the terms of the contract request a maximum of 216 animals available for contraceptive testing.

In any event, the entry of January 27, 1993, is the only one referring to electroejaculation in the records reviewed for 25205.

The electroejaculation came almost precisely on 25205’s third anniversary at CRPRC.

On February 9, an entry says that 25205 has been reported for dehydration again, but that he may just naturally appear to be dehydrated due to his dark eyes and skin.

On February 21, he is seen again for a wound to his right hand.

On March 5, he is reported to have loose stool again.

In almost every entry through June 19, 25205 is reported to have “loose stool,” “stool partially liquid,” or “liquid stool.” On the 19th, he is reported to be vomiting as well.

July 2: “depression. Not confirmed.”

July 29: “Variable stool and vomit confirmed.”

This continues throughout the rest of the year. And on February 2, 1994, he is reported to be depressed.

On March 30 1994, 25205 is tattooed again.

On April 4, the entry notes that a tech had reported that 25205 had lacerations on his left arm. The person making the entry says that these wounds seem old and superficial, and that there was not any swelling.

On May 11, he is seen again for another wound to his left hand.

On September 11, this entry appears: “.6cc Ket. Abrasion to (L) forearm. Animal may have gnawed himself. Wound was very superficial & old, was already scabbing over. Shaved area cleaned wound w/DNS & applied granulex. Monitor healing. Should heal fine by itself.”

On September 12, it is noted that he is vomiting.

On November 2, he is again treated for wounds to his left arm. It is noted that he has a history of wounding in this area. They note that he still has his canine teeth and that this “may lead to problems.” They request that his canine teeth be cut down and suggest that research services be notified of 25205’s “possible stereotypic behavior.”

Stereotypic behavior is behavior believed to be outside the norm for caged animals. It is a problem in the primate labs of epidemic proportion. One study at the New England Regional Primate Research Center reported that ten percent of the monkeys at that institution (a part of Harvard University) injured themselves severely enough as to require veterinary intervention. [M. A. Novak, J. H. Kinsey, M. J. Jorgensen, T. J. Hazen.1998. Effects of puzzle feeders on pathological behavior in individually housed rhesus monkeys. American Journal of Primatology ;46(3):213-27.]

Stereotypic behaviors include self-biting and other self-mutilations, bizarre movements such as endless twirling and jumping and the repetitive pacing common in many caged animals. In the Oregon undercover video a very young isolated monkey is curled into a ball sucking his penis.

Interestingly, researchers variously claim that the causes of such behavior are largely unknown; while others claim that most such behaviors are eliminated when monkeys are able to touch one another. These behaviors are essentially unknown among wild or group-housed primates. Only the primate research laboratories are unable to make the logical inference: primates caged alone go insane.

On November 26, 1994, 25205 is seen for another wound. This time a small wound on the tip of the second finger of his right hand.

On December 7, he is reported to be vomiting again.

December 29: “Reported for self-trauma to (L) forearm. .7cc ket. Traumatic lacerations to both forearms. (L) forearm has small 1&Mac218;2 cm full-thickness skin laceration – not involving underlying muscle. Cleaned and sutured…surrounding tissue has multiple bruises and contusions. (R) forearm has ~ 1cm full-thickness skin laceration with minor trauma to underlying muscle. Cleaned and sutured….monitor for future evidence of self-trauma.”

The following day it is noted that the sutures have been pulled out and the bandages are gone. But, the wounds seem to be “healing well.” [An overnight miracle?]

On January 2, it is noted that both arms seem to still be healing but that right arm’s suture site is swollen and appears moist.

On January 30, 1995, 25205’s five year anniversary at CRPRC, he is reported to have mild abrasions on his right hand.

On February 7, his stool is again noted to be of varied consistency.

On April 6, they performed a “pulpotomy” on his upper canine teeth and blunted his lower canines.

On April 17, he was reported again for “self-trauma” to his left arm. He had been biting his arm near his wrist.

Entries through April 24 note that the wound is healing well.

On May 21, he is treated again for a new wound to his left forearm.

On the following day, 25205 is anesthetized for a tuberculosis test. The wound on his arm is treated. A sore is discovered under the collar he has apparently had on for over two years. The entry notes: “Had sore on neck from too tight collar. Collar removed.”

Treatment continues for the wound on his arm. On May 26, it is noted that the wound has fresh blood on it and that he seems to have been biting himself again. Throughout this time, the wound was being treated with the common wound dressing, Granulex. It is suggested that the Granulex may be irritating the wound and maybe that’s why he continues to chew on himself. They switch to aloe vera.

25205 licks off the aloe vera.

The wound continues to be treated with aloe vera spray. On June 5, it is noted that the wound has nearly healed and that the skin has grown in well.

On June 22, he is reported to have reopened an old wound on the tip of a finger of his right hand.

On October 26, he is reported to be vomiting again.

On November 14, 25205 has diarrhea again. And again on April 19, 1996. And on April 22. And then, on April 23, his stool is reported to me scant, very bloody and with mucus.

On November 24, it is reported that no parasites can be found.

On June 13, he has loose stool again. This continues through the 21st when he is again reported to be vomiting.

Every entry through August 16 comments on his loose stool. Many tests are run and nothing is diagnosed.

On September 28, he is again seen for self-inflicted trauma: “Abrasions, bruising, and inflammation of (L) proximal forearm – self-inflicted.” The wound is treated.

October 3, 1996: “Noted recent trauma to both arms most noticeable on the (L) forearm. Continue to monitor. If new trauma is observed reassess. Also notify enrichment coordinator.”

October 8. He is reported to have liquid stool. Minor trauma to his left forearm is again noted. On October 9, he is vomiting again.

On October 14, an entry says that his wounds are healing well, and that his diarrhea is self-limiting. He is discharged from medical care.

November 2, and he is again vomiting.

On January 22, he again is reported to have liquid stool.

It is noted on January 28 that his diarrhea is persistent. More lab tests come back negative.

On January 30, 1997, after seven years at CRPRC, the entry reads, “Maintaining well.”

The diarrhea persists. On February 7, 1997 someone enters the comment, “Diarrhea self-limiting.”

On June 16, 25205 is again seen and treated for wounds to both forearms. They are described as superficial contusions and abrasions.

June 24: “Rept. for arm trauma. The trauma was observed on the (R) arm and was superficial & did not appear inflamed or infected animal has [history] of self-trauma to arms. Notify enrichment coordinator. Monitor closely. Assess for anti-anxiety [medication].”

On July 10, 25205’s teeth are again “cut down” as a cure for his self-biting.

On July 23, he again is reported for loose stool and vomiting.

The loose stool persists, more negative lab tests, more monitoring.

October 11: “reported arm trauma confirmed. 1 small puncture wound to (L) medial proximal forearm. No redness, bleeding or swelling. Observed grooming arm. Possible self-trauma to arm. Monitor.”

October 15. Liquid stool confirmed.

More diarrhea throughout the rest of the month. On October 30, they start treating 25205 with Flagyl (Metronidazole), a common medicine for various gastric parasites.

On November 2, he is vomiting again.

On November 4, there is no sign of diarrhea and on November 9, the notation is made: “Resolved diarrhea.”

November 17. Reported for liquid stool.

On November 24, 25205 is reported to have a poor appetite.

On January 7, the liquid stool is continuing and he is vomiting again. A note is made that should the liquid stool persist, that some should be collected and sent to the lab, and that he should be monitored for more vomiting, and that, if his condition remains the same, a referral should be made to the vet.

The diarrhea continues. On January 20, 1998, the notation is made that the diarrhea is “nonpathogenic” and that the he should continue to be monitored.

On January 22, someone suggests that they try anti-inflammatory steroids if the ‘condition persists.”

The liquid stool persists intermittently throughout the ensuing months. 25205 continues to vomit occasionally. On June 15, 1998, and again on October 19, he is subjected to some experimental procedure – probably an injection of some kind. The details are blacked out. CRPRC claims this is due to “verbal and physical harassment, including death threats, which have been made against these individuals [involved in the research].”

On December 12, he is reported to still be experiencing loose stools and to have a poor appetite.

On March 15, he is reported with neck trauma. A scab on his right hand is noted. It is all considered as minor and no treatment is pursued.

On August 8, 1999, a note is made that he has loose stool. A comment is included that suggests this is because he received raisins as an enrichment the day before.

On January 14, 2000, 25205 is again seen for trauma to his arms. It is noted that this is presumed to be self-inflicted.

January 21: “Reported fore arm trauma. Confirmed. Gave .5 cc Ketamine to evaluate wound. (L) fore arm have numerous superficial bite wounds as well as to (L) bicep.” (sic) The wounds were treated. It was noted that the wounds were self-inflicted. The observer notes that 25205 is a “self-biter” and suggests that they should try to “make animal busy through enrichment.”

On February 8, 9 and 10, he is reported with more diarrhea.

On February 25, there is more trauma to his left arm.

More diarrhea. On May 11, he is vomiting again.

Between May 11, and August 12, 2000, the last record available for 25205, 26 daily entries are recorded. All of them deal with the fact that he has diarrhea.

Chronic diarrhea is epidemic in the primate labs.

25205’s life has been one of chronic illness. The stress of a caged existence has caused him to bite himself and chew on his own arms repeatedly. His capture, incarceration, and misery have served no purpose to humans other than providing jobs to cage cleaners and veterinarians. Those who claim that animals in laboratories are well-treated, respected, and irreplaceable to modern medical research are ignorant of the facts concerning the actual lives of the animals about whom they comment. Literally tens-of-thousands of monkeys such as 25205 are suffering through similar lives today in taxpayer supported laboratories across the country precisely because of the deafening silence from the public regarding their plight. If this silence is an artifact of the public’s ignorance, hopefully 25205’s miserable life and story might serve to educate.

25205, our thoughts are with you.


Primate Freedom Project
P.O. Box 1623
Fayetteville, GA. 30214
Tel: 678.489.7798


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